Alemtuzumab approved by NICE

Alemtuzumab is now approved in England (from 28 May 2014) and Scotland (7 July 2014) as a treatment for adults with active relapsing remitting multiple sclerosis on the NHS (with funding approved by NHS England on 9 September 2014). This liberal approval represents a significant change in the way drugs for multiple sclerosis are approved; responsibility for deciding who gets alemtuzumab is being handed over to patients and their doctors. People with relapsing-remitting multiple sclerosis now have the option of an aggressive therapy early in their illness. This is not for everyone, and we urge caution on the behalf of doctors and patients considering alemtuzumab treatment. But we are pleased this is now an option. Alemtuzumab is now also licensed in Canada, Argentina, Australia, Brazil and Mexico. On November 14th 2014, it was also licensed in the US for “patients who have had an inadequate response to two or more drugs indicated for the treatment of MS”. See here. For our latest publication on the long-term effects of alemtuzumab, see here.

Trials in multiple sclerosis

We are still actively recruiting for a trial of alemtuzumab in relapsing- remitting multiple sclerosis (”CAMTHY”) in the UK. More information on this trial can be found here: for people with multiple sclerosis; for doctors We are also making progress for a trial of bexarotene in multiple sclerosis as a potential remyelinating agent. Alasdair Coles December 2014
© Website designed by Alasdair Coles, 2012
Home Alemtuzumab Group Members Research For People with MS Contact News YOUR HEADING TEXT Alasdair Coles, Joanne Jones and Alastair Compston  Cambridge Neuroimmunology
“We are very pleased to be able to recommend alemtuzumab for adults with relapsing-remitting multiple sclerosis. Evidence has shown that alemtuzumab is more effective and less expensive than current similar treatments for those with severe relapsing- remitting MS. The NICE Committee heard from clinical specialists and patients during the appraisal process who described alemtuzumab as a revolutionary treatment for some people, allowing them to live their lives as they had before their diagnosis.” Sir Andrew Dillon, NICE Chief Executive 28 May 2014
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